Research

There is a critical need to develop novel therapeutic strategies for CRC and OS. Immunotherapy is dramatically changing how we treat patients with cancer, however, it is only effective when immune cells are actively recognize and fight the cancer.

Our lab focuses on understanding the molecular mechanisms that regulate anti-tumor immune response in cancers. Currently we are investing the following topics in our laboratory.

1. Tumor-derived extracellular vesicles and anti-tumor immunity in colorectal cancer

2. Atypical chemokine receptor 4 (ACKR4) in anti-tumor immunity in colorectal cancer

3. MicroRNAs mediate host-microbiome interactions in colorectal cancer progression

4. Regulation of host immune response in osteosarcoma